400016 Certifying Courses in Biotech: Isotope Methodology, Radiation Protection, Laboratory Animal Science

Details
Department of Natural Sciences   75 %
Department of Veterinary Pathobiology   25 %
Earliest Possible Year
DurationOne block
 
Credits7.5 (ECTS)
Course LevelJoint BSc and MSc
The course is application oriented and a prerequisite for working within radioactive isotopes and/or lab. animal science.
 
ExaminationFinal Examination

written examination


Written Exam in Lecturehall

All aids allowed

Description of Examination: The purpose of the 4 hour written exam is to document that the course participators are sufficiently qualified to conduct safe experimental work within isotope methodology, radiation protection and laboratory animal science. The exam will consist of text-based problems as well as short exercises and questions.

Weight: 25% within lab animal science 75% within Isotope Methodology and Radiation Protection



13-point scale, external examiner

Dates of Exam:
27 January 2006
 
Requirement For Attending ExamParticipation in lab exercises and approved reports from lab exercises
 
Organisation of TeachingThe theory will be given as lectures (2 times 2 hours per week) and theoretical case work (2 times 2 hours per week), and Lab. exercises (1 times 4 hours per week).
 
Block PlacementBlock 2
Week Structure: B
 
Teaching LanguageEnglish
 
Optional PrerequisitesBiophysics, Statistics, Basic Chemistry
 
Restrictionsmax 32 students (Due to limited laboratory facilities in the isotope lab.).
 
Areas of Competence the Course Will Address
Competencies within Basic Sciences:
IM+RP: Understanding of fundamental theory for radioactivity (RA), sources of RA, interaction between RA and matter (biological tissue), detection of radioactivity and the applications of RA isotopes in scientific experiments
LAS: The student will achieve a knowledge of animal experimentation

Competencies within Applied Sciences:
IM+RP: Apply above mentioned principles and theory in Laboratory work with radioactivity, incl. safe laboratory practice.
LAS: The student will achieve knowledge about animal experimentation

Competencies within Ethics and values
IM+RP: The student will be aware of ethical concerns related to working with radioactivity.
LAS: The student will be aware of the moral discussion on the use of live animals for research.
 
Course Objectives
The goal is give a broad introduction to theory and practical work within the fields of IM+RP and LAS.

The IM+RP course is accredited by "Statens Institut for Strålehygeine" and graduates from the course will obtain a certificate that allows them to work independently with radioactive isotopes.

The LAS course is accredited by the Ministry of Justice according to Ministerial Order No 1016, §2, which will allow graduates from this course to participate in animal experiments under another persons license.
 
Course Contents
IM+RP: the course includes the following topics:
-Introduction to atomic and nuclear physics, isotopes and radiation
-Decay of isotopes and radioactivity, half life,
-Interaction of radiation with matter
-Introduction to safe laboratory practice
-Counting and statistics
-Health physics
-Radiation safety
-Radiotracer methods
-Nuclear reactions, production, activation
-Medical and biological use of isotopes incl. imaging
-Nuclear physics and life
-Stable isotopes
-Danish legislation concerning work with open radioactive sources

LAS: The course includes the following topics: Ethical, welfare, and legislative aspects of using animals for research; biology, husbandry, genetics, breeding, anaesthesia and analgesia of laboratory animals. Main focus will be on rodents

 
Teaching And Learning Methods
IM+RP: Theory: Self study of literature combined with presentation and discussion of theory during lectures, calculation of exercises and theoretical analysis of problems and cases. Laboratory exercises (incl. approval of reports), followed by oral group presentations of selected laboratory exercises at plenary sessions. The course will be carried out in collaboration with the Radiation Research Department at Risø National Laboratory and one or more laboratoryexercises will take place at Risø. LAS: The theory will be given as lectures and 1 colloquium, while handling and experimental techniques will be practiced on live animals. Some self study of literature must be expected
 
Course Litterature
IM+RP:
Ehmann & Vance: Radiochemistry and Nuclear Methods of Analysis , Wiley Interscience.

Sundhedsstyrelsen, Statens Institut for Strålehygiejne: Vejledning om strålebeskyttelse ved arbejde med åbne radioaktive kilder.

Handouts and exercise manuals to be placed on the course homepage.

LAS:
An international textbook on laboratory animal science as well as handouts and exercise manuals to be placed on the course homepage.
 
Course Coordinator
Lise Arleth, lia@life.ku.dk, Department of Natural Sciences/Biophysics, Phone: 35332317
Axel Kornerup Hansen, akh@life.ku.dk, Department of Veterinary Pathobiology/Section for Biomedicine, Phone: 35332726
 
Attendance Fee
To be decided
 
Study Board
Study Committee NSN
 
Course Scope
lectures36
theoretical exercises32
practicals32
preparation102
examination4

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