280007 Bioprocessing Technologies

Detaljer
Inst. for Grundvidenskab
Tidligst mulig placering
VarighedEn blok
 
Pointværdi7.5 (ECTS)
KursustypeKandidatkursus
 
EksamenSluteksamen

skriftlig og mundtlig eksamen


Alle hjælpemidler tilladt

Beskrivelse af eksamen: Evaluation of reports of performed experiments supplemented with oral presentations and examination

Vægtning: Reports are judged by 60 % and oral presentation and examination are judged by 40 %



13-skala, intern censur
 
Forudsætninger for indstilling til eksamenAcceptance of reports over initial experimental exercises
 
Rammer for undervisningThe course consists of a combined theoretical part (lectures and theoretical exercises; approx. 6h/week) and practical laboratory work (approx. 9h/week). Visit to companies using biotech/bioprocessing technologies (one day) will be part of the course.
 
BlokplaceringBlock 3
Ugestruktur: A
 
UndervisningssprogEngelsk
med note om undervisning på dansk
 
Anbefalede forudsætninger230002 Biokemi 1
230006 Enzymology and Experimental Biochemistry
Biochemistry 1 Enzymology and experimental biochemistry
 
Begrænset deltagerantalThe number of students per course is limited to 30 owing to limited space in the laboratories and the need for intensive teaching in use of advanced instrumentations.
 
Kompetenceområder
Basic Science:
Knowledge to theory behind new bioprocessing technologies

Transfer of theory from laboratory experiments to use of the technologies in Pilot Plant scale and in industrial production

Applied Science:
Knowledge to development of strategies for bioprocessing technologies

Apply principles from laboratory experiments to large-scale productions of added value products, especially products from agricultural crops and products

Ethics and Values:
Respond and reflects on environmental related problems in processing technologies
 
Kursets målsætning
The course provides a thorough and fundamental theoretical and practical introduction to understanding of the effects processing technologies may have on quality and value of end products. Focus will be placed on environmental friendly bioprocessing technologies to production of added value / high quality products. Chemotaxonomic occurrence of the actual allelochemicals, advantages and disadvantages of new and traditional technologies, including economy, will be evaluated in the course.
 
Kursusindhold
The course comprises teaching in the theoretical basis for bioprocessing technologies closely linked with experimental work using methods and technologies required to obtain the necessary knowledge to structures and physico-chemical-biochemical properties of actual biomolecules and the starting materials under consideration. With bioprocessing technologies variations are especially in the types of starting materials of interest and in the relevant methods and techniques which can be used, depending on whether the goals for the technologies are productions of pure high value specialty products/biomedicine/bioactive natural products or whether the aim is bulk productions of high quality concentrates or isolates of lipids, proteins/bioactive proteins/enzymes, carbohydrates or other biomolecules for feed, food and non-food applications. In the case where specialty products with high prices and high degree of purity are the aim, it is possible to use more expensive and time consuming technologies, whereas productions of bulk products give limits in the actual or relevant technologies which can be used. Common for both types of bioprocessing technologies is the need for knowledge gained by laboratory experiments, and transfer of the optimised technologies to Pilot Plant scale and from there to final and economical viable industrial productions.
The course includes evaluations and studies of obstacle from bioactive molecules reducing the product quality, and in the case of plants as chemical factories for the starting materials, chemotaxonomic studies are important. This is also the case where the aim is bulk production of added value products as concentrates of lipids, proteins and carbohydrates from actual agricultural or horticultural crops by use of environmentally friendly techniques. Bioprocessing technologies of such types are based on environmental "green chemistry" processes using aqueous/enzyme aided systems, high pressure/temperature controlled techniques, supercritical fluid techniques based on CO2 as fluid and with limited use of harmful chemicals.
The course gives knowledge to:
· Experimental detection of actual sources to proteins, enzymes, lipids, carbohydrates/dietary fibres and occurrence of bioactive natural products of relevance for agroindustrial productions and by use of "plants as chemical factories" and for productions of bioactive natural products, fine chemicals, for plant and feed/food protections or as biomedicines.
· Laboratory scale development of strategies for optimal bioprocessing technologies and required analytical methods needed to optimisation of processing steps, processing control and to documentation of product quality and authenticity.
· Industrial production and use of enzymes; proteases, carbohydrases, lipases etc.
· Product quality testing and evaluation.
· Restrictions, limitations and possibilities in bioprocessing technologies.
· Application of environmentally friendly processing techniques and creation of added value products.
· Concerns and opportunities for working in the field between research and production scale.
· Introduction to and practical knowledge on use of advanced production and analytical instruments.
· Unit operations used in bioprocessing technologies including filtrations, separations, extractions, chromatography
 
Undervisningsform
Lectures and theoretical exercises: lectures will be used to present the theoretical background for the subjects considered with use of at least 2 hours per week and following the progress in the study program and experimental work. The lectures will be followed by theoretical exercises where the students in groups of three will work on evaluation of the descriptions in original literature, on answers to specific questions related to the theory and to the practical application and use of methods and technologies. Laboratory work aiming at learning the students knowledge to transfer of theory to practical use of the various instruments, biochemical methods, and technologies relevant for bioprocessing technologies are central parts of the course. The students will be in groups of three and spend about 9 hours per week with this part of the course. The last 2/3 of the course period will be devoted to a large project focused on a specific bioprocess technology. This project will be chosen among a selection of subjects, and agreed on by the students and the teacher. The combined theoretical and practical laboratory experiments with focus on strategies of actual technologies will train the students in calculations and evaluations of produced data, statistical analyses of obtained results, quality assurance and reporting with evaluation of processing effects on product quality based on own data in relation to literature data.
 
Litteraturhenvisninger
G. Walsh (2002): Proteins, Biochemistry and Biotechnology. John Wiley and Sons Ltd. West Sussex, UK (ISBN 0-471-899070

H.Sørensen, S.Sørensen, C.Bjergegaard og S.Michaelsen (1999): Chromatogrphy and Capillary Electrophoresis in Food Analysis. Royal Society of Chemistry, Cambridge, UK. ( ISBN 0-85404-561-9)

Selection of new original scientific papers
 
Kursusansvarlig
Hilmer Sørensen, hils@life.ku.dk, Institut for Grundvidenskab/Biokemi og naturproduktkemi, Tlf: 35332432
Jens Christian Sørensen, jchs@life.ku.dk, Institut for Grundvidenskab/Biokemi og naturproduktkemi, Tlf: 35332435
 
Studienævn
Studienævn NSN
 
Kursusbeskrivelsesomfang
forelæsninger20
teoretiske øvelser30
praktiske øvelser60
forberedelse84
ekskursioner10
eksamen2

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