270058 Thematic Course: Process Analytical Technology

Details
Department of Food Science
Earliest Possible YearMSc. 1 year to MSc. 2 year
DurationTwo blocks
 
Credits15 (ECTS)
Course LevelMSc
 
ExaminationFinal Examination

oral examination


All aids allowed

Description of Examination: The students will work in groups and hand in a written report in due time before the oral examination. At the individual oral examination the students will be examined in the report as well as the examination requirements.

Weight: Oral examination: 100 %



7-point scale, external examiner
 
Requirement For Attending ExamParticipation in group project work as well as approval of report
 
Organisation of TeachingLectures, seminars and projects
 
Block PlacementBlock 3
Week Structure: A

Block 4
 
Teaching LanguageEnglish
 
Optional Prerequisites270002 Advanced Chemometrics with MATLAB
270028 Quantitative Food Spectroscopy
270059
 
Restrictions50
 
Areas of Competence the Course Will Address
Competences within applied science:
The student will understand the process of solving real-world PAT problems by collaborating with industries and by seeking problem-specific resources at uiniversities and industry. The student will learn to define a process related problem, point out possible solutions, choose a suitable possible solution and investigate the feasibility of this. The student will acquire knowledge on quality control, on-line measurements, applied chemometrics, process control and validation. During the project, the students will learn to handle the following aspects in an industrial environment

. Problem definition
. Process description
. Experimental design
. Sampling issues incl. design of sampling
. Measurement technology
. Validation
. Reference measurements
. On-line analysis
. Calibration and model building
. Calibration transfer
. Calibration maintenance
. Process control

 
Course Objectives
To learn scientific approaches to solving complex real-world PAT problems. The theme course will show the student how the individual competences (process understanding, chemometrics and statistics, GxP, sensors) are brought into providing a solution when combined with real-world constraints and goals in an industrial setting.
 
Course Contents
Apart from learning scientific approaches to solving real-world problems, the student will learn to appreciate the more basic but important problems appearing when dealing with projects in industry. E.g. issues such as inadequate measures of quality, non-identified critical points, and poor sampling strategies.

Depending on the specific problem dealt with, the thematic course will incorporate several of the aspects mentioned below:

. Problem definition
. Process description
. Experimental design
. Sampling issues incl. design of sampling
. Measurement technology
. Validation
. Reference measurements
. On-line analysis
. Calibration and model building
. Calibration transfer
. Calibration maintenance
. Process control

The above items are taught through self-study, tutoring and lectures. The course also includes mandatory common aspects that are taught in lessons and used in the practical part of the project. These common aspects are determination of critical control points and GxP including an understanding of the legislative and regulatory framework in industry.
 
Teaching And Learning Methods
The course includes one weekly module with lectures and seminars. The seminars will include theoretical problems that the students are to investigate through scientific literature and are to present implications of for their current project. The projects will deal with different aspects of the course subject. The project work will be carried out in groups of 3-4 students and will include literature studies and experimental work preferably with an industrial partner. The project work will result in a report that is presented orally at a seminar at the end of the course.
 
Learning Outcome
Stipulated in "Areas of Competence the Course Will Address"
 
Course Litterature
Scientific papers and chapters from relevant books.
 
Course Coordinator
Rasmus Bro, rb@life.ku.dk, Department of Food Science/Quality and Technology, Phone: 35333296
 
Study Board
Study Committee LSN
 
Course Scope
lectures25
project work341
supervision10
Colloquia16
preparation12
examination8

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