240037 Basic Pharmacology and Toxicology

Detaljer
Inst. for Sygdomsbiologi
English titleBasic Pharmacology and Toxicology
Tidligst mulig placeringKandidat 1.år
VarighedEn blok
 
Pointværdi7.5 (ECTS)
KursustypeKandidatkursus
 
EksamenSluteksamen

skriftlig prøve


Skriftlig auditorieeksamen

Alle hjælpemidler tilladt

Beskrivelse af eksamen: 4 hour written exam with essey type questions and short questions. Pocket calculator necessary.

Vægtning: Written exam: 100%



7-trinsskala, ekstern censur

Eksamensdatoer:
24 January 2009
 
Rammer for undervisningThe course consists of lectures, theoretical exercises and case studies.
 
BlokplaceringBlock 2
Ugestruktur: C
 
UndervisningssprogEngelsk
 
Obligatoriske forudsætningerBachelor in biotechnology
 
Begrænset deltagerantalNone
 
Kursusindhold
The course consists of lectures, exercises and cases. Lectures cover the following areas:

1. General pharmacology
2. Drug targets
3. The drug development process
4. General toxicology
5. The drug-manufacturing process

The lectures are supported by exercises and cases in the same topics.
 
Undervisningsform
The course consists of lectures and teoretical case studies. In particular the case studies will require some self study and homework.
 
Målbeskrivelse
The main objective in basic pharmacology and toxicology is to provide an introduction to pharmacokinetics (absorption, distribution, metabolism, excretion) and pharmacodynamics including dose / response relationships. In toxicology the in vitro and in vivo test methods are introduced and the estimation of threshold levels. Identification of biomarkers and target molecules and organs will also be included. Examples of different chemical groups and their targets, toxicity, and risks are discussed

Knowledge

- Describe basic pharmacological and toxicological principles
- List drug targets
- Summarize the drug development process
- Describe in vitro and in vivo toxicity tests - threshold levels
- Identify targets for toxicity and biomarkers


Skills


- Apply correct pharmacological and toxicological terminologies
- Explain pharmacological and toxicological principles
- Demonstrate knowledge of toxicological testing
- Analyze test results
- Estimate threshold levels and assess risks


Competences

- Discuss basic pharmacological and toxicological principles
- Perform basic pharmacokinetic calculations
- Apply toxicological tests to identify target for toxicity and find threshold levels
- Discuss risk
- Evaluate biomarkes and their use (pharmacological and toxicological)
 
Kursusansvarlig
Mette Tingleff Skaanild, mts@life.ku.dk, Institut for Veterinær Patobiologi/Faggruppen for Biomedicin, Tlf: 35333175
Jens Lykkesfeldt, jopl@life.ku.dk, Institut for Sygdomsbiologi/Faggruppen for Biomedicin, Tlf: 35333163
 
Studienævn
Studienævn NSN
 
Kursusbeskrivelsesomfang
forelæsninger40
teoretiske øvelser60
eksamen4
forberedelse102

206