240039 Plant Genomics

Detaljer
Institut for Jordbrug og Økologi   45 %
Institut for Plantebiologi og Bioteknologi   45 %
Institut for Basal Husdyr- og Veterinærvidenskab   10 %
English titlePlant Genomics
Tidligst mulig placeringBachelor 2. år til Kandidat 2. år
VarighedEn blok
 
Pointværdi7.5 (ECTS)
KursustypeFælleskursus
 
EksamenSluteksamen

skriftlig prøve


Skriftlig auditorieeksamen

Alle hjælpemidler tilladt

Beskrivelse af eksamen: A four hours written examination

Vægtning: 100 %



7-trinsskala, intern censur

Eksamensdatoer:
23. juni 2010
 
Forudsætninger for indstilling til eksamenAccepted lab reports(75 %) and oral presentation of case
 
Rammer for undervisningTeaching includes a mix of lectures, laboratory and computer exercises complemented by cases for student groups. Laboratory work demonstrates selected key issues in plant genomics. Computer exercises demonstrate the potential of internet resources.
 
BlokplaceringBlock 1
Ugestruktur: A

Block 4
Ugestruktur: A, The course is offered two times during the study year 2009/2010
 
UndervisningssprogEngelsk
 
Anbefalede forudsætninger240032 
240007 Bioinformatik 1
 
Begrænset deltagerantalNone
 
Kursusindhold
Forward and reverse genetics.
Gene- and genome duplication and polyploidity
Mutants including: TILLING/T-DNA/transposon/spontaneous.
Genome and EST sequencing programs - why particular model organisms have been chosen.
Genetic diversity of plants.
Phylogenetic trees, pedigrees and dendrograms based on molecular markers and gene sequences.
Structure and evolution of plant genomes.
Molecular marker based maps and linkage analysis.
Quantitative traits and their genetics (QTL).
Comparative mapping of plant genomes and the exploitation of synteny.
Functional genomics.
Multi gene families in plants: emphasis on cytochromes P450 and MYB transcription factors
In vitro culture of plants and plant regeneration.
DNA microarray expression profiling in higher plants: analysis and applications
Comparative genomics and syntheny.
 
Undervisningsform
40 % for lectures and discussion classes. 60 % for practical exercises and supervised case studies. Students are expected to work in groups for their exercises and cases and to be able to produce written and oral presentations of their results.
 
Målbeskrivelse
The course will provide basic understanding of the structure and evolution of plant genomes and central techniques used for studies of genomes and molecular breeding through a combination of lectures, cases, wet-lab exercises and computer exercises. Focus will be on the relationship between phenotypic traits and genotypes using the expanding information and resources on plant genomes and RNA/DNA/protein sequences. The course begins with the genomics and central techniques and databases developed for the two main plant model species, rice and Arabidopsis, and translates the principles to cultivated crops to understand the potential and constraints of applying genomic technology for plant breeding.

After completing the course the students should be able to:

Knowledge
- Describe basic principles for the study of major model plants and general plant evolution.
- Classify genetic markers and their use for qualitative and quantitative traits
- Describe basic central experimental techniques used in plant genomics and molecular breeding.

Skills
- Integrate basic knowledge on plants to understand complex biological processes using plant model systems.
- Apply molecular and genetic tools for plant improvement through molecular breeding of crops for food, fodder and production of high value crops for e.g. biomedicine, biofuel, green factories, etc.

Competences
- Evaluate various forward and reverse genomics approaches for gene isolation and functional studies.
- Relate gene differences with phenotype by means of genomics
- Discuss the ethical aspects of the use of new molecular approaches in plant biotechnology e.g in relation to biodiversity.
 
Litteraturhenvisninger
Laboratory manuals, selected scientific publications, and text book
 
Kursusansvarlig
Sven Bode Andersen, sba@life.ku.dk, Institut for Jordbrug og Økologi/Plante- og Jordvidenskab, Tlf: 35333444
Kirsten Jørgensen, kij@life.ku.dk, Institut for Plantebiologi og Bioteknologi/Plantebiokemisk Laboratorium, Tlf: 35333346
 
Studienævn
Studienævn NSN
 
Kursusbeskrivelsesomfang
forelæsninger20
teoretiske øvelser20
praktiske øvelser65
eksamen4
forberedelse97

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