240051 Immunology

Details
Responsible DepartmentDepartment of Veterinary Disease Biology

Earliest Possible YearMSc. 1 year
DurationOne block
 
Credits15 (ECTS)
 
Level of CourseMSc
 
ExaminationFinal Examination

written examination


Written Exam in Lecturehall

No aid allowed

Description of Examination: 4 hours written exam.

Weight: Written exam: 100%



7-point scale, internal examiner

Dates of Exam:
03 November 2010
 
Requirement for Attending ExamApproved practical course and at least 80% attendance.
Submission of reports
 
Organisation of Teachinglectures, problem discussions, practical laboratory course (amounts to nine full days) including report writing and problem solving
 
Block PlacementBlock 1
Week Structure: A

Block 1
Week Structure: B
 
Language of InstructionEnglish
 
Optional Prerequisites230002 Biochemistry 1
240009 Cell Biology
 
Restrictionsmax. 30
 
Course Content
The theoretical part will cover modern immunology, with special emphasis on the current research areas of interest to the biotech industry.
The course will cover the basic principles of the immune system and its regulation and give an updated insight into modern molecular immunology.

The practical course will focus on modern immunological techniques, which apart from basic techniques, will include cultivation and purification of lymphocytes from blood, flow cytometry and molecular signaltransduction techniques.

 
Teaching and learning Methods
Lectures, problem solving, practical course (nine day incl. report writing).
 
Learning Outcome
The objective is to provide the student with an updated knowledge about immunology and the immune system.
The course will cover key elements in the development, activation and regulation of the innate and adaptive immunune system.
In the end of the course we will focus on diseases caused by lack immune regulation. This will include Allergy, Autoimminity and Cancer and the current/future treatment strategies.

The practical course will cover a variety of currently used molecular cellular immunological-techniques, which can also be used in non-immunological research. The practical course will also include critical reading and discussion of original research articles.

Knowledge:
- Describe the cells and structural building of the immune system.
- Understand how the Innate immune system works, including creation of inflammation and specific ways of patogen recognition and phagocytosis.
- Understand the basic principles that controls adaptive immunity, including development of antigen specific receptors (TCR and BCR), nature and function of MHC molecules, activation and regulation of T and B cells, development of immunological memory.
- Insight in the molecular signal regulation of immunity, including cytokines and intracellular signal mechanisms.
- Describe the function of the immune system during, autoimmunity, allergy, immune defects, transplantation and cancer.
- Perform immunological experiments, including critical evaluation of the results.

Skills:
Use immunologically founded reasoning on various scientific problems concerning health and related issues.
Use various immunologically and molecular techniques to solve questions raised in immunology and related fields.

Competences:
Have acquired knowledge to discuss immunological literature, immunological problems, techniques and an updated knowledge of molecular immunology - both basic and more specialised areas.
Have a technical foundation to suggest experimental analysis of some immunological questions.
 
Course Literature
Janeway's Immunobiology. Murphy, Travers, Walport. 2008. 7ed Garland.

Manuals for practical course in Immunology.
 
Course Coordinator
Søren Skov, sosk@life.ku.dk, Department of Veterinary Disease Biology/Section for Biomedicine, Phone: 353-33126
 
Study Board
Study Committee NSN
 
Work Load
lectures32
theoretical exercises48
practicals68
preparation260
examination4

412