| Responsible Department | Department of Veterinary Disease Biology | ||||||||||||
| Earliest Possible Year | MSc. 1 year | ||||||||||||
| Duration | One block | ||||||||||||
| Credits | 7.5 (ECTS) | ||||||||||||
| Level of Course | MSc | ||||||||||||
| Examination | Final Examination written examination Written Exam in Lecturehall All aids allowed Description of Examination: 4 hour written exam with essey type questions and short questions. Pocket calculator necessary. Weight: Written exam: 100% 7-point scale, external examiner Dates of Exam: 26 January 2012 | ||||||||||||
| Organisation of Teaching | The course consists of lectures, theoretical exercises and case studies. | ||||||||||||
| Block Placement | Block 2 Week Structure: A | ||||||||||||
| Language of Instruction | English | ||||||||||||
| Mandatory Prerequisites | Bachelor in biotechnology | ||||||||||||
| Restrictions | None | ||||||||||||
| Course Content | |||||||||||||
| The course consists of lectures, exercises and cases. Lectures cover the following areas: 1. General pharmacology 2. Drug targets 3. The drug development process 4. General toxicology 5. The drug-manufacturing process The lectures are supported by exercises and cases in the same topics. | |||||||||||||
| Teaching and learning Methods | |||||||||||||
| The course consists of lectures and teoretical case studies. In particular the case studies will require some self study and homework. | |||||||||||||
| Learning Outcome | |||||||||||||
| The main objective in basic pharmacology and toxicology is to provide an introduction to pharmacokinetics (absorption, distribution, metabolism, excretion) and pharmacodynamics including dose / response relationships. In toxicology the in vitro and in vivo test methods are introduced and the estimation of threshold levels. Identification of biomarkers and target molecules and organs will also be included. Examples of different chemical groups and their targets, toxicity, and risks are discussed Knowledge - Describe basic pharmacological and toxicological principles - List drug targets - Summarize the drug development process - Describe in vitro and in vivo toxicity tests - threshold levels - Identify targets for toxicity and biomarkers Skills - Apply correct pharmacological and toxicological terminologies - Explain pharmacological and toxicological principles - Demonstrate knowledge of toxicological testing - Analyze test results - Estimate threshold levels and assess risks Competences - Discuss basic pharmacological and toxicological principles - Perform basic pharmacokinetic calculations - Apply toxicological tests to identify target for toxicity and find threshold levels - Discuss risk - Evaluate biomarkes and their use (pharmacological and toxicological) | |||||||||||||
| Course Coordinator | |||||||||||||
| Leon Brimer, lbr@life.ku.dk, Department of Veterinary Disease Biology/Section for Biomedicine, Phone: 353-33181 Alan Steen Norddal Mortensen, alanm@dsr.life.ku.dk, Department of Veterinary Disease Biology/Section for Biomedicine, Phone: 353-33165 | |||||||||||||
| Study Board | |||||||||||||
| Study Committee NSN | |||||||||||||
| Work Load | |||||||||||||
| |||||||||||||