LKEF10076 Analytical Chemistry

Details
Responsible DepartmentDepartment of Basic Science and Environment   80 %
Department of Food Science   6 %
Department of Agriculture and Ecology   14 %

Earliest Possible YearBSc. 3 year to MSc. 2 year
DurationOne block
 
Credits7.5 (ECTS)
 
Level of CourseJoint BSc and MSc
 
ExaminationFinal Examination

written examination and oral examination


Written Exam in Lecturehall

All aids allowed

Description of Examination: 3 hours written examination and 15 - 20 min oral examination of practical aspects of analytical chemistry. The latter is based on the laboratory exercises

Weight: The written exam 2/3. Oral examination of practical aspects 1/3.



7-point scale, internal examiner

Dates of Exam:
10 April 2012
 
Requirement for Attending ExamMinimum 75% of the reports from the laboratory exercises need to be accepted by the course teacher before final examination.
 
Organisation of TeachingThe teaching comprises lectures (28 h), seminars (8 h) theoretical exercises (28 h) and laboratory exercises (24 h). A one-day excursion will be included (8 h).
 
Block PlacementBlock 3
Week Structure: C
Wednesday afternoons. The participants will be divided into laboratory teams. Some of these teams will have laboratory exercises outside the normal course module.

 
Language of InstructionEnglish
 
Restrictions120 students
 
Course Content
The course topics include: An introduction to analytical chemistry: choice of analytical methodology, sampling, sample preparation, chemical analysis, tools for quantitative chemical analysis, quality assurance. Extraction methods such as liquid-liquid extraction, solid phase extraction, super-critical fluid extraction and accelerated solvent extraction. Cleanup and fractionation methods. Introduction to Chromatography, high-pressure liquid chromatography (HPLC), gas chromatography (GC) and other chromatographic methods. Detector types with focus on mass spectrometry and hyphenated techniques such as GC-MS and LC-MS. Introduction to spectroscopic methods (UV-VIS, IR, X-ray, atomic absorption spectroscopy (AAS) and inductive coupled plasma mass spectrometry). Introduction to data processing, errors in chemical analyses, statistical analyses (including chemometrics) and data presentation. Method development, evaluation, validation and QA/QC measures.

Compulsory laboratory exercises comprise projects which involve sampling, extraction and cleanup, methods of analysis, data processing and data evaluation.
 
Teaching and learning Methods
Lectures and theoretical exercises: The lectures will present the general chemical background of the measurement principles and instrumental techniques as well as theory on sampling, data processing, data analysis, quality assurance and method validation. Theoretical exercises: These exercises will train the students to carry out calculations on the data produced from different instrumental techniques including statistical analyses, reporting and QA/QC. Laboratory exercises: Laboratory exercises represent the heart of the course. Here, the participants train the different instrumental techniques and get used to analytical work in the laboratory. The laboratory exercises comprise 6 compulsory themes. Theoretical and laboratory exercises are performed by groups of 2 or 3 students. A 1-day excursion to a larger accredited laboratory is included in the course.
 
Learning Outcome
The course objective is to introduce the participants to modern instrumental techniques and analytical approaches within environmental- and soil chemistry, food chemistry and plant biology.

After completing the course the student should be able to:

Knowledge:
Describe the theory of sampling, sample preparation and sample preparation techniques
Refer to the chemical theory behind the use of modern instrumental techniques for quantitative chemical analysis
Describe how to identify unknown compounds by mass spectrometry and to measure their concentrations in environmental and food samples

Skills:
Develop and apply methods for separating chemical compounds in mixtures using chromatography
Perform quantitative chemical analysis of organic compounds and metals
Apply solid data processing and evaluation of analytical data

Competences:
Develop, validate and apply analytical methods in different field of research
Evaluate and discuss analytical chemical data from the literature.
Do problem solving in analytical chemistry
 
Course Literature
Daniel C. Harris (Eight edition): Quantitative Chemical Analysis.

Course teachers: Compendium for laboratory exercises, handouts and electronic resources

 
Course Coordinator
Jan H. Christensen, jch@life.ku.dk, Department of Basic Sciences and Environment, Phone: 353-32456
Søren Husted, shu@life.ku.dk, Department of Agriculture and Ecology/Plant and Soil Science, Phone: 353-33498
Karsten Olsen, ko@life.ku.dk, Department of Food Science/Food Chemistry, Phone: 353-33201
 
Study Board
Study Committee NSN
 
Work Load
lectures28
theoretical exercises28
practicals24
Excursions8
examination4
preparation106
Colloquia8

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