LPhD144 Introduction to nutritional metabolomics

Details
Responsible DepartmentDepartment of Human Nutrition   75 %
Department of Food Science   25 %

Research SchoolFOOD Denmark

The course is supported by SYSDIET (www.sysdiet.fi) and will be posted through NuGO (www.nugo.org), OPUS (www.foodoflife.dk/Opus/English.aspx) and UNIK - Food, Fitness and Pharma(http://foodfitnesspharma.ku.dk/).
 
Course Dates5 to 9 December 2011.
 
Course AbstractThe course gives an introduction to the nutritional metabolomics pipeline from study design over sample collection, storage and analysis over data alignment and analysis using different softwares to data interpretation. A small training trial will be conducted during the course for the students to work on.
 
Course RegistrationSign up for the course to Marianne Støckel (mas@life.ku.dk).
 
Deadline for RegistrationBefore 1 November 2011. We will assign students in the order they sign up.
 
Credits3 (ECTS)
There will be at least one week preparatory work with article reading.
 
Level of CoursePhD course
 
Organisation of TeachingThe course will be mainly a class course with minimal hands-on in the laboratory. The students must bring their own computers running Windows XP or higher.
 
Language of InstructionEnglish
 
RestrictionsThe course will be limited to 20 participants.
 
Course Content
The couse plan will be posted at the SYSDIET and NuGO homepages (www.sysdiet.fi and www.nugo.org). This introductory course in nutritional metabolomics will take the student through all steps in a typical study. This will include study design considerations, sample collection and handling, spectroscopic techniques for metabolic profiling, analytical quality control, data collection and preprocessing, data alignment and processing, statistical data treatments, and interpretation of the final data outcomes.

A major focus is on the use of various free or commercial softwares for data alignment, data analysis, and data interpretation with hands-on training based on a case with samples collected by the students during the course.

The course will finalize by presentations of reports generated by the students based on their own results from the case.
 
Teaching and learning Methods
The couse will use a mixture of lectures, exercises and training with data generated by the students during the course.
 
Learning Outcome
The aim of this course is to introduce the student to all phases in a nutritional metabolomics study and to train the student in the use of available softwares for data handling and data analysis. Specific aims include,
1) to teach how study design affects sample and data handling
2) to teach the most common free softwares for working with metabolomics data and nutritional bioinformatics
3) To teach common strategies for marker identification
 
Course Material
A list of references to be read prior to the course will be sent to the participants.
 
Course Coordinator
Thaer Ali Mustafa Barri, thbar@dsr.life.ku.dk, Department of Human Nutrition/Preventive Nutrition, Phone:
Lars Ove Dragsted, ldra@life.ku.dk, Department of Human Nutrition/Preventive Nutrition, Phone: 353-32694
 
Other Lecturers
Søren B Engelsen, Francesco Savaroni, Gözde Gürdeniz, Flemming Hoffman Larsen, Rasmus Bro, Christian Ritz and Martina Kutmon.
 
Course Fee
A course fee of 175? to be paid by all participants. Invoice will be sent after registration is made.
 
Course Costs
Each student must pay and arrange their own travel and accommodation in Copenhagen during the course.
 
Type of Evaluation
Oral presentation of results.
 
Work Load
lectures18
theoretical exercises12
preparation35
project work12

77

 
Other Remarks
Foods will be provided for the students, but travel and accommodation have to be handled individually by the students.